We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
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Most Useful Reviews
9
Joint relief
6 people found this helpful
This complex works wonders for bone and joint health. After just a week, I noticed a reduction in the unpleasant clicks and creaks in my knees that I'd suffered from for an extended period.
Read More
9
Leg pain relief
1 people found this helpful
After consuming calcium and vitamin D3, I've noticed my nails no longer exfoliate, and my leg pain has vanished, as have the cramps.
Read More
7.5
Supports bone health
1 people found this helpful
The quality of the product supports and enhances bone health. The packaging is sufficient for approximately three months. The taste is somewhat acceptable. Before each use, I add a prayer to the Prophet, asking God for benefits and protection from any harm.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Joint relief
6 people found this helpful
This complex works wonders for bone and joint health. After just a week, I noticed a reduction in the unpleasant clicks and creaks in my knees that I'd suffered from for an extended period.
Read More
9
Leg pain relief
1 people found this helpful
After consuming calcium and vitamin D3, I've noticed my nails no longer exfoliate, and my leg pain has vanished, as have the cramps.
Read More
7.5
Supports bone health
1 people found this helpful
The quality of the product supports and enhances bone health. The packaging is sufficient for approximately three months. The taste is somewhat acceptable. Before each use, I add a prayer to the Prophet, asking God for benefits and protection from any harm.
Read More
9
Very good supplement
Suitable for older adults, it strengthens bones and improves vitamin D deficiency. It's an excellent supplement with an acceptable taste. It supports calcium absorption and vitamin D levels, lasting around four months. Overall, it’s a wonderful blend, but drinking plenty of water is essential.
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6
Bone healing aid
2 people found this helpful
I really liked these vitamins! After breastfeeding, I found my bones weakened, leading to a fingertip fracture. I started on this complex, and thanks to it, my plaster was removed after only two weeks instead of a month!
Bone pain is a discomfort or ache that originates within the bones themselves and can range from mild to severe. It is different from muscle or joint pain, as it directly affects the skeletal structure. Bone pain can be caused by a variety of factors, including injuries, medical conditions such as osteoarthritis or osteoporosis, infections, or tumors. Symptoms may vary depending on the underlying cause but often include a dull, penetrating ache that may worsen with movement or pressure.
If you're experiencing persistent bone pain, it’s essential to consult with a healthcare professional for a proper diagnosis and treatment plan. Imaging tests like X-rays, MRI, or CT scans may be utilized to determine the root cause of the pain. Treatment can vary widely, ranging from medications to alleviate pain and inflammation to physical therapy or, in some cases, surgical interventions. Understanding the underlying cause is crucial to effectively managing bone pain and ensuring the best path to recovery.
Calcium is a chemical element represented by the symbol Ca and atomic number 20. It is an essential mineral in the body, playing a critical role in various physiological processes. As one of the most abundant elements in nature, calcium is particularly vital for maintaining strong bones and teeth, where about 99% of the body's calcium is stored. Beyond its structural function, calcium is crucial in muscle contraction, blood clotting, and nerve transmission, making it a key player in overall health.
Dietary sources of calcium include dairy products such as milk, yogurt, and cheese, as well as leafy green vegetables, nuts, seeds, and fortified foods. The recommended daily intake of calcium varies by age and sex, but generally, adults should aim for approximately 1,000 mg per day. For those who may struggle to meet their needs through diet alone, calcium supplements are available but should be taken with caution. It's essential to consult with a healthcare provider before starting any supplement regimen to avoid potential side effects or interactions with medications.
Calcium is an essential mineral that plays a critical role in maintaining bone health and strength. Adequate calcium intake is crucial for the prevention of various bone-related issues, including osteopenia and osteoporosis, conditions that can lead to increased bone pain and fractures. When the body does not receive enough calcium, it may start to leach this mineral from the bones, potentially leading to weakness and pain. Therefore, ensuring you meet your daily calcium requirements can contribute to healthier bones and may, in turn, help alleviate some types of bone pain associated with deficiencies.
However, it's essential to note that while calcium is fundamental for bone health, it may not directly relieve bone pain caused by other factors such as injury, arthritis, or other medical conditions. For those experiencing chronic bone pain, incorporating calcium-rich foods into your diet—such as dairy products, leafy greens, and fortified foods—should be part of a broader approach that includes medical evaluation and potential treatment options. Consulting a healthcare professional is advised to determine the underlying causes of bone pain and to develop a comprehensive plan that may include dietary adjustments, exercise, and medications if necessary.
Based on user reviews, the timeframe for seeing results from bone pain supplements can vary, but many users report positive outcomes within a short period. For instance, one user noted a significant reduction in knee discomfort after just one week of use Read Review. Another user shared their experience of having bone pain alleviated within two weeks while taking the supplement alongside daily walking Read Review.
Several reviews highlight that noticeable improvements, such as the resolution of leg pains and cramps or a reduction in discomfort, can manifest within a few weeks. It's also common for users to report benefits such as enhanced bone health and less overall discomfort over a longer period, often described around a month or two Read Review. As with any supplement, results may vary individually, but many users seem to agree that consistent use leads to positive outcomes relatively quickly.
This supplement may have some indirect support for bone pain relief, particularly in cases related to intravenous iron infusions. A study investigated the effects of calcium treatment on patients who developed osteomalacia due to these infusions. In this study, patients received phosphate, calcium, and active Vitamin D supplementation after discontinuing ferric carboxymaltose infusions, which had caused low phosphate levels and pain. Researchers noted improvements in biochemical markers and reductions in pain scores; however, they emphasized that the specific contribution of calcium to these outcomes could not be isolated from the overall treatment regimen that included multiple supportive measures [1].
While the findings suggest that calcium may play a role in a broader treatment context, definitive evidence directly linking calcium supplementation to reduced bone pain is lacking. Future research would be necessary to clarify the exact relationship between calcium and bone pain relief in various clinical scenarios. As it stands, individuals considering calcium supplements for bone pain should consult healthcare providers for tailored advice based on their specific conditions.
Based on user reviews, many individuals report significant improvements in their symptoms after using bone and joint health supplements. For example, one user noted a reduction in the audible clicks and creaks in their knees after just one week of use Read Review. Others have experienced a more comprehensive alleviation of symptoms, with reports of leg pain and cramps disappearing after incorporating calcium and vitamin D3 into their regimen Read Review.
Additionally, users have highlighted improvements beyond just pain relief. One reviewer shared that after starting the supplement, their recovery time from a fingertip fracture was unexpectedly shorter, with the plaster removed in two weeks instead of a month Read Review. Many individuals also mention enhanced overall well-being and relief from back pain, indicating a strong connection between these supplements and bone health Read Review. While anecdotal experiences suggest a trend of positive results, it’s important to remember that individual experiences can vary.
Based on user reviews, many individuals report positive experiences when combining this supplement with other supplements for addressing bone pain. Specifically, some users have noted that incorporating calcium and vitamin D3 together has led to significant improvements in their symptoms, including the disappearance of leg pain and cramps Read Review. Another user highlighted the importance of pairing calcium intake with vitamin D3 for optimal absorption, emphasizing that this combination is particularly beneficial in preventing osteoporosis and addressing deficiencies Read Review.
Additionally, several reviews indicate that the synergistic effects of these nutrients not only aid in pain relief but also support overall bone health. One reviewer mentioned how the combination of these supplements has not only improved their bone pain but also rejuvenated their overall well-being Read Review. Another noted a significant decrease in back pain after taking the supplement in conjunction with physical activity Read Review. Overall, users seem to advocate for the effectiveness of combining specific supplements to maximize benefits for bone health and pain management.
Based on user reviews, it appears that a combination of calcium and vitamin D3 is highly regarded for alleviating bone pain and improving overall bone health. For instance, one user reported that after taking a calcium and vitamin D3 supplement, their leg pain and cramps disappeared, indicating significant relief from discomfort Read Review. Another user noted that these supplements supported calcium absorption effectively, which is crucial for addressing deficiencies and improving bone strength, especially in older adults Read Review.
Furthermore, several reviews highlight that regular consumption of calcium, paired with vitamin D, is vital for maintaining bone health as one ages. Users reported noticeable improvements in bone pain and overall well-being after incorporating these supplements into their routine Read Review. It's essential to ensure that calcium is combined with vitamin D for optimal absorption and efficacy in treating bone-related issues. As such, regular intake seems to be an effective strategy for those dealing with bone pain.
9
Joint relief
6 people found this helpful
This complex works wonders for bone and joint health. After just a week, I noticed a reduction in the unpleasant clicks and creaks in my knees that I'd suffered from for an extended period.
7.5
Back pain reduction
2 people found this helpful
These well-formulated calcium tablets are intended to supplement calcium and vitamin D3 deficiencies. After taking them for two weeks while walking daily, my back no longer aches, and I sleep soundly. They're quite affordable for a comprehensive calcium supplement.
9
Leg pain relief
1 people found this helpful
After consuming calcium and vitamin D3, I've noticed my nails no longer exfoliate, and my leg pain has vanished, as have the cramps.
6
Bone healing aid
2 people found this helpful
I really liked these vitamins! After breastfeeding, I found my bones weakened, leading to a fingertip fracture. I started on this complex, and thanks to it, my plaster was removed after only two weeks instead of a month!
7.5
Prevents calcium deficiency
I highly recommend these tablets. The key lies in the combination of D3 with trace elements, which enhance vitamin efficacy. I take calcium to prevent osteoporosis and deficiencies in bone tissues, ensuring it’s taken with vitamin D3 for optimal absorption.
9
Significant improvement
As one ages, it's essential to regularly consume calcium to strengthen bones. This supplement contains calcium and vitamin D, which are better absorbed together, addressing deficiencies. I've noticed a significant improvement in my well-being regarding bone pain. The packaging is convenient, but I'm not fond of the taste. A notable advantage is the affordable price, and the quality of delivery is always excellent.
9
Very good supplement
Suitable for older adults, it strengthens bones and improves vitamin D deficiency. It's an excellent supplement with an acceptable taste. It supports calcium absorption and vitamin D levels, lasting around four months. Overall, it’s a wonderful blend, but drinking plenty of water is essential.
8
Calcium's role in bone pain unclear
In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution.
We explored the impact of calcium treatment on bone pain in patients who developed osteomalacia, a condition linked to intravenous iron infusions. Our focus was on a group of 13 patients diagnosed with this condition, who experienced low phosphate levels due to excess fibroblast growth factor 23 (iFGF23) after receiving ferric carboxymaltose (FCM) infusions.
After halting the FCM infusions, these patients were given supportive treatment, which included phosphate, calcium, and active Vitamin D supplementation. We observed improvements in biochemical markers, including increased phosphate levels and reduced pain scores. However, it’s important to note that while calcium was part of the treatment regimen, we could not isolate its specific effects on bone pain from the other supportive measures used.
Ultimately, our findings highlight the importance of monitoring phosphate levels in patients receiving FCM, and stopping these infusions effectively addresses phosphate wasting. Although supportive treatment showed improvements in pain and bone density, the direct impact of calcium on bone pain remains unclear given the combination of treatments involved.
References
von Brackel FN, Grambeck J, Barvencik F, Amling M, Oheim R. In-depth clinical characterization of intravenous iron infusion-induced hypophosphatemic osteomalacia and its resolution. JBMR Plus. 2024;8:ziae139. 10.1093/jbmrpl/ziae139